Surrozen (NASDAQ:SRZN – Get Free Report) and Soleno Therapeutics (NASDAQ:SLNO – Get Free Report) are both medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, risk, earnings, analyst recommendations, valuation, dividends and institutional ownership.
Valuation and Earnings
This table compares Surrozen and Soleno Therapeutics”s gross revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Surrozen | $10.65 million | 19.70 | -$63.56 million | ($22.34) | -1.10 |
| Soleno Therapeutics | N/A | N/A | -$175.85 million | ($1.84) | -20.24 |
Insider and Institutional Ownership
66.6% of Surrozen shares are owned by institutional investors. Comparatively, 97.4% of Soleno Therapeutics shares are owned by institutional investors. 43.5% of Surrozen shares are owned by company insiders. Comparatively, 6.4% of Soleno Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.
Analyst Ratings
This is a summary of current recommendations and price targets for Surrozen and Soleno Therapeutics, as reported by MarketBeat.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Surrozen | 1 | 0 | 1 | 1 | 2.67 |
| Soleno Therapeutics | 1 | 1 | 12 | 1 | 2.87 |
Surrozen currently has a consensus target price of $32.00, suggesting a potential upside of 30.72%. Soleno Therapeutics has a consensus target price of $110.62, suggesting a potential upside of 197.03%. Given Soleno Therapeutics’ stronger consensus rating and higher possible upside, analysts clearly believe Soleno Therapeutics is more favorable than Surrozen.
Volatility and Risk
Surrozen has a beta of 0.58, meaning that its share price is 42% less volatile than the S&P 500. Comparatively, Soleno Therapeutics has a beta of -3.16, meaning that its share price is 416% less volatile than the S&P 500.
Profitability
This table compares Surrozen and Soleno Therapeutics’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Surrozen | -2,909.10% | -4,055.04% | -88.90% |
| Soleno Therapeutics | N/A | -25.88% | -19.84% |
Summary
Soleno Therapeutics beats Surrozen on 8 of the 13 factors compared between the two stocks.
About Surrozen
Surrozen, Inc., a clinical stage biotechnology company, discovers and develops drug candidates to selectively modulate the Wnt pathway for tissue repair. The company is developing antibody-based therapeutics which targets various disease areas, including diseases of the intestine, liver, retina, cornea, lung, kidney, cochlea, skin, pancreas, and central nervous system. Its products in pipeline include SZN-043, a hepatocyte-specific R-spondin mimetic bispecific fusion protein, which is in Phase 1b clinical trial for the treatment of severe liver diseases, including alcohol-associated hepatitis. The company develops SZN-413, a Fzd4 targeted bi-specific antibody for the treatment of retinal vascular associated diseases. Surrozen, Inc. has collaboration and license agreement with Boehringer Ingelheim International GmbH to research, develop, and commercialize Fzd4 bi-specific antibodies. Surrozen, Inc. is based in South San Francisco, California.
About Soleno Therapeutics
Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead candidate is Diazoxide Choline Extended-Release tablets, a once-daily oral tablet, which is in Phase III clinical trials for the treatment of Prader-Willi Syndrome. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was incorporated in 1999 and is based in Redwood City, California.
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