Celldex Therapeutics (NASDAQ:CLDX – Get Free Report) and 4D Molecular Therapeutics (NASDAQ:FDMT – Get Free Report) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, profitability, analyst recommendations, institutional ownership, dividends, valuation and risk.
Risk & Volatility
Celldex Therapeutics has a beta of 0.9, meaning that its share price is 10% less volatile than the S&P 500. Comparatively, 4D Molecular Therapeutics has a beta of 2.75, meaning that its share price is 175% more volatile than the S&P 500.
Analyst Ratings
This is a summary of current ratings and recommmendations for Celldex Therapeutics and 4D Molecular Therapeutics, as provided by MarketBeat.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Celldex Therapeutics | 1 | 1 | 11 | 0 | 2.77 |
| 4D Molecular Therapeutics | 1 | 1 | 11 | 0 | 2.77 |
Celldex Therapeutics currently has a consensus price target of $63.08, indicating a potential upside of 115.67%. 4D Molecular Therapeutics has a consensus price target of $28.90, indicating a potential upside of 167.59%. Given 4D Molecular Therapeutics’ higher possible upside, analysts clearly believe 4D Molecular Therapeutics is more favorable than Celldex Therapeutics.
Valuation & Earnings
This table compares Celldex Therapeutics and 4D Molecular Therapeutics”s top-line revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Celldex Therapeutics | $1.54 million | 1,491.56 | -$258.76 million | ($4.35) | -6.72 |
| 4D Molecular Therapeutics | $85.21 million | 7.00 | -$140.11 million | ($2.63) | -4.11 |
4D Molecular Therapeutics has higher revenue and earnings than Celldex Therapeutics. Celldex Therapeutics is trading at a lower price-to-earnings ratio than 4D Molecular Therapeutics, indicating that it is currently the more affordable of the two stocks.
Profitability
This table compares Celldex Therapeutics and 4D Molecular Therapeutics’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Celldex Therapeutics | N/A | -52.35% | -47.61% |
| 4D Molecular Therapeutics | -194.74% | -41.33% | -35.90% |
Institutional and Insider Ownership
99.3% of 4D Molecular Therapeutics shares are held by institutional investors. 5.2% of Celldex Therapeutics shares are held by company insiders. Comparatively, 7.9% of 4D Molecular Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.
Summary
4D Molecular Therapeutics beats Celldex Therapeutics on 9 of the 11 factors compared between the two stocks.
About Celldex Therapeutics
Celldex Therapeutics, Inc., a biopharmaceutical company, engages in developing therapeutic monoclonal and bispecific antibodies for the treatment of various diseases. Its drug candidates include antibody-based therapeutics to treat patients with inflammatory, allergic, autoimmune, and other devastating diseases. The company’s clinical development programs CDX-0159, a Phase II monoclonal antibody that binds the receptor tyrosine kinase KIT and inhibits its activity. It has research collaboration and license agreements with Yale University. The company was incorporated in 1983 and is headquartered in Hampton, New Jersey.
About 4D Molecular Therapeutics
4D Molecular Therapeutics, Inc., a clinical-stage biotherapeutics company, develops genetic medicines using its therapeutic vector evolution platform in the Netherland and the United States. The company develops a portfolio of genetic medicine product candidates focuses in three therapeutic areas for ophthalmology, cardiology, and pulmonology. Its product pipeline includes 4D-150, which is in phase 1/2 clinical trial for the treatment of wet age-related macular degeneration; and is in phase 1/2 clinical trial for the treatment of diabetic macular edema. The company develops 4D-125, which is in phase 1/2 clinical trial for the treatment of x-linked retinitis pigmentosa; 4D-110, which is in phase 1/2 clinical trial for the treatment of choroideremia; 4D-710, which is in phase 1/2 clinical trial for the treatment cystic fibrosis lung disease; and 4D-310 to treat fabry disease cardiomyopathy and is in phase 1/2 clinical trial. In addition, its product candidates comprises 4D-175, which is in pre-clinical development for the treatment for geographic trophy; and 4D-725 to treat alpha-1 antitrypsin deficiency lung disease and is in pre-clinical development. The company has collaboration and licensing agreements with Arbor Biotechnologies, Inc.; Astellas Gene Therapies, Inc; uniQure biopharma B.V.; and Cystic Fibrosis Foundation. 4D Molecular Therapeutics, Inc. was founded in 2013 and is headquartered in Emeryville, California.
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