Head-To-Head Review: Twist Bioscience (NASDAQ:TWST) and Regenxbio (NASDAQ:RGNX)

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Twist Bioscience (NASDAQ:TWST) and Regenxbio (NASDAQ:RGNX) are both small-cap medical companies, but which is the better stock? We will compare the two businesses based on the strength of their profitability, dividends, institutional ownership, risk, valuation, earnings and analyst recommendations.

Earnings and Valuation

This table compares Twist Bioscience and Regenxbio’s revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Twist Bioscience $25.43 million 28.06 -$71.23 million ($25.51) -1.00
Regenxbio $218.51 million 8.62 $99.94 million $2.38 21.61

Regenxbio has higher revenue and earnings than Twist Bioscience. Twist Bioscience is trading at a lower price-to-earnings ratio than Regenxbio, indicating that it is currently the more affordable of the two stocks.

Profitability

This table compares Twist Bioscience and Regenxbio’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Twist Bioscience N/A N/A N/A
Regenxbio -41.99% -9.90% -9.35%

Insider and Institutional Ownership

21.4% of Twist Bioscience shares are owned by institutional investors. Comparatively, 81.5% of Regenxbio shares are owned by institutional investors. 13.8% of Regenxbio shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Analyst Recommendations

This is a summary of recent ratings and target prices for Twist Bioscience and Regenxbio, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Twist Bioscience 0 1 3 0 2.75
Regenxbio 1 1 5 0 2.57

Twist Bioscience presently has a consensus target price of $26.33, suggesting a potential upside of 3.44%. Regenxbio has a consensus target price of $84.18, suggesting a potential upside of 63.68%. Given Regenxbio’s higher possible upside, analysts plainly believe Regenxbio is more favorable than Twist Bioscience.

Summary

Regenxbio beats Twist Bioscience on 8 of the 13 factors compared between the two stocks.

About Twist Bioscience

Twist Bioscience Corporation, a synthetic biology company, manufactures and sells synthetic DNA-based products. The company's DNA synthesis platform enables the manufacturing of synthetic DNA by writing DNA on a silicon chip. It offers synthetic DNA-based products, including synthetic genes, tools for sample preparation, antibody libraries for drug discovery and development, and DNA as a digital data storage medium. Twist Bioscience Corporation has a collaboration agreement with Pandion Therapeutics, Inc. to apply its antibody optimization platform for a targeting arm of a bispecific antibody. The company was founded in 2013 and is headquartered in San Francisco, California.

About Regenxbio

REGENXBIO Inc., a clinical-stage biotechnology company, provides gene therapy product candidates to deliver genes to cells to address genetic defects or to enable cells in the body to produce therapeutic proteins or antibodies that are intended to impact disease. Its gene therapy product candidates are based on NAV Technology Platform, a proprietary adeno-associated virus (AAV) gene delivery platform. The company's lead product candidate is RGX-314, which is in Phase I/IIa clinical trials for the treatment of wet age-related macular degeneration. It is also developing RGX-121 that is in Phase I/II clinical trials to treat mucopolysaccharidosis type II; RGX-111 for treating mucopolysaccharidosis type I; RGX-181 for the treatment of late infantile neuronal ceroid lipofuscinosis type II disease; and RGX-501, which is in Phase I/II clinical trials to treat homozygous familial hypercholesterolemia. REGENXBIO Inc. also licenses its NAV Technology Platform to other biotechnology and pharmaceutical companies. The company was formerly known as REGENX Biosciences, LLC and changed its name to REGENXBIO Inc. in September 2014. REGENXBIO Inc. was founded in 2008 and is headquartered in Rockville, Maryland.

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